Publications before independence

Liu, F., Mailhot, O., Glenn, I.S., Vigneron, S.F., Bassim, V., Xu, X., Fonseca-Valencia, K., Smith, M.S., Radchenko, D.S., Fraser, J.S., Moroz, Y.S., Irwin, J.J., Shoichet, B.K. (2025), The impact of library size and scale of testing on virtual screening. Nature Chemical Biology.

Liu, F.*, Wu, C.*, Tu, C., Glenn, I., Meyerowitz, J., Kaplan, A.L., Lyu, J., Cheng, Z., Tarkhanova, O.O., Moroz, Y.S., Irwin J.J., Chang, W., Shoichet, B.K., Skiniotis, G. (2024). Large library docking identifies positive allosteric modulators of the calcium-sensing receptor. Science 385, eado 1868.

Liu, F.*, Kaplan A.L.*, Levring, J.*, Einsiedel, J.*, Tiedt, S., Distler, K., Omattage, N.S., Kondratov, I.S., Moroz, Y.S., Irwin, J.J., Gmeiner, P., Shoichet, B.K., Chen, J. (2024). Structure-based discovery of positive and negative CFTR modulators. Cell 187, 3712-3725 e3734.

Liu, F., Lee, J., and Chen, J. (2021). Molecular structures of the eukaryotic retinal importer ABCA4. Elife 10.

Liu, F.*, Zhang, Z.*, Levit, A., Levring, J., Touhara, K.K., Shoichet, B.K., and Chen, J. (2019). Structural identification of a hotspot on CFTR for potentiation. Science 364, 1184-1188.

Zhang, Z.*, Liu, F.*, and Chen, J. (2018). Molecular structure of the ATP-bound, phosphorylated human CFTR. Proc Natl Acad Sci U S A.

Zhang, Z., Liu, F., and Chen, J. (2017). Conformational changes of CFTR upon phosphorylation and ATP binding. Cell 170, 483-491 e488.

Liu, F.*, Zhang, Z.*, Csanady, L., Gadsby, D.C., and Chen, J. (2017). Molecular structure of the human CFTR ion channel. Cell 169, 85-95 e88.

Gorelik, A., Liu, F., Illes, K., and Nagar, B. (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. J Biol Chem 292, 7087-7094.